Buy now and earn up to $3,500 in savings on your January 2026 order

Shop and save

Hamburger Menu Button
Thermo Fisher Scientific Logo
Sign in
Don't have an account ? Create Account
  • Products
    • Antibodies
    • Cell Culture Media
    • Chemicals
    • Chromatography Columns and Cartridges
    • Lab Equipment
    • Lab Plasticware and Supplies
    • Microplates
    • Oligos, Primers, Probes and Genes
    • TaqMan Real-Time PCR Assays
    • Greener Products
    • See all product categories
  • Applications
    • Bioprocessing
    • Cell Culture and Transfection
    • Cell and Gene Therapy
    • Chromatography
    • Molecular Testing
    • Digital Solutions
    • DNA and RNA Extraction and Analysis
    • Spectroscopy, Elemental and Isotope Analysis
    • See all applications and techniques
  • Services
    • 360° CDMO and CRO Solutions
    • CDMO Services
    • CRO Services
    • Custom Services
    • Enterprise Services
    • Financial and Leasing Services
    • Instrument Services
    • Lab Informatics
    • OEM and Commercial Supply
    • Training Services
    • Unity Lab Services
    • See all services
  • Help and Support
    • How to Order
    • Instrument Support
    • Learning Centers
    • Register for an Account
    • Technical Support Centers
    • See all help and support topics
  • Popular
    • TaqMan Real-Time PCR Assays
      TaqMan Real-Time PCR Assays
    • Antibodies
      Antibodies
    • Oligos, Primers & Probes
      Oligos, Primers & Probes
    • GeneArt Gene Synthesis
      GeneArt Gene Synthesis
    • Cell Culture Plastics
      Cell Culture Plastics
  • Who We Serve
    • Biotech
    • Biopharma
    • CDMO
    • Lab Diagnostics
    • Industrial and Applied Sciences
  • Promotions
  • Contact Us
  • Quick Order
  • Order Status and Tracking
  • Documents and Certificates
Thermo Fisher Scientific Logo

Search

Primary Antibodies
  • Search All
  • Popular Product Areas
  • TaqMan Assays
  • Primary Antibodies
  • Secondary Antibodies
  • Isotype Controls
  • Proteins & Peptides
  • ELISA Kits
  • All Documents & Support
  • Certificates
  • SDS
  • Manuals & Protocols
  • Product FAQs
    Search button
            Target, gene symbol, antigen
            Application
            Target Species
            • Order Status
            • Quick Order
            • Promos
            • Sign in
              Sign in
              Don't have an account ? Create Account
              • Account
              • Check Order Status
              • Aspire Member Program
              • Connect: Lab, Data, Apps
              • Custom Products & Projects
              • Services Central

            Disclaimer

            Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

            Loading ...
            • Primary Antibodies ›
            • OPRM1 Antibodies

            Invitrogen

            Phospho-OPRM1 (Ser375) Polyclonal Antibody

            1 Reference
            View all (33) OPRM1 antibodies

            Promotions

            View available promotion(s)

            Promo Code: RGLOW25 Save up to $900 and get the limited-edition holiday sweatshirt + matching beanie It’s been a year – this is your badge of honor for fluorescing through it all. Offer available until December 27.. Learn more

            Spend Now, Save Big Later! Spend Now, Save Big Later! Make your New year's resolution to save: earn up to $3,500 off a future January offer when you purchase a qualifying amount before December 31st. Learn more

            Datasheet
            Protocols
            Questions & Answers
            Catalog # PA5-17698
            Web quote
            You can generate a web quote (PDF) by signing in to your account and adding products to your cart. View cart and click the 'Generate a web quote' button. With your web quote document, you can get approval for your order and complete your order online.
             
            Price (USD)
            365.25
            Special offer
            Online exclusive
            Ends: 13-Dec-2025
            487.00
            Save 121.75 (25%)
            100 µL
             
            Check your price
            Request bulk or custom format
            Join Aspire™ for free antibodies
            Datasheet
            Protocols
            Questions & Answers

            Cite Phospho-OPRM1 (Ser375) Polyclonal Antibody

            Phospho-OPRM1 (Ser375) Polyclonal Antibody

            Product Details

            PA5-17698

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:1,000
            View 1 publication 1 publication

            Immunocytochemistry (ICC/IF)

            1:200
            -

            Immunoprecipitation (IP)

            1:100
            -
            Product Specifications

            Species Reactivity

            Human, Mouse

            Published species

            Mouse

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Synthetic phosphopeptide corresponding to residues surrounding pSer377 of human (homologous to pSer375 of mouse) µ-opioid receptor
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            54.1 µg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

            Contains

            no preservative

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_10983814

            Product Specific Information

            It is not recommended to aliquot this antibody.

            Target Information

            The OPRM1 gene encodes the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            Bioinformatics

            Protein Aliases: hMOP; KIAA0403; M-OR-1; MOP; MOP receptor; MOR-1C; Mu opiate receptor; Mu opioid receptor; mu opioid receptor hMOR-1a; mu opioid receptor splice variant mMOR-1Z; Mu-type opioid receptor; Opioid mu receptor; Opioid Receptor; opioid receptor, mu 1; OTTHUMP00000017463

            View more View less

            Gene Aliases: LMOR; M-OR-1; MOP; MOP-R; MOR; MOR-1; MOR-1O; MOR1; muOR; OPRM; OPRM1

            View more View less

            UniProt ID: (Human) P35372, (Mouse) P42866

            View more View less

            Entrez Gene ID: (Human) 4988, (Mouse) 18390

            View more View less

            Function(s)

            G-protein alpha-subunit binding G-protein coupled receptor activity beta-endorphin receptor activity voltage-gated calcium channel activity protein binding protein C-terminus binding protein domain specific binding filamin binding G-protein beta-subunit binding morphine receptor activity neuropeptide binding signal transducer activity opioid receptor activity G-protein coupled receptor transmembrane signal receptor

            Process(es)

            acute inflammatory response to antigenic stimulus G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger adenylate cyclase-activating dopamine receptor signaling pathway negative regulation of adenylate cyclase activity phospholipase C-activating G-protein coupled receptor signaling pathway neuropeptide signaling pathway chemical synaptic transmission sensory perception locomotory behavior negative regulation of cell proliferation response to radiation sensory perception of pain adenylate cyclase-inhibiting opioid receptor signaling pathway response to food positive regulation of appetite response to lipopolysaccharide cellular response to stress wound healing response to cocaine eating behavior estrous cycle behavioral response to ethanol positive regulation of neurogenesis regulation of sensory perception of pain excitatory postsynaptic potential negative regulation of Wnt protein secretion positive regulation of ERK1 and ERK2 cascade calcium ion transmembrane transport response to growth factor cellular response to morphine regulation of N-methyl-D-aspartate selective glutamate receptor activity signal transduction G-protein coupled receptor signaling pathway adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway positive regulation of cytosolic calcium ion concentration negative regulation of cAMP biosynthetic process opioid receptor signaling pathway positive regulation of cAMP-mediated signaling negative regulation of cAMP-mediated signaling negative regulation of nitric oxide biosynthetic process positive regulation of nitric oxide biosynthetic process response to ethanol negative regulation of cytosolic calcium ion concentration
            It has to be done as per old AB suggested Products section.
            guarantee_icon

            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

            Learn more
            help_icon

            We're here to help

            Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

            Contact tech support
            Ordering Plus Icon Minus Icon
            • Order Status
            • Order Help
            • Quick Order
            • Supply Center
            • eProcurement
            Support Plus Icon Minus Icon
            • Help and Support
            • Contact Us
            • Technical Support Centers
            • Documents and Certificates
            • Report a Site Issue
            Resources Plus Icon Minus Icon
            • Learning Centers
            • Promotions
            • Events and Webinars
            • Social Media
            About Thermo Fisher Plus Icon Minus Icon
            • About Us About Us
            • Careers Careers
            • Investors Investors
            • News News
            • Social Responsibility Social Responsibility
            • Trademarks
            • Consumer Health Data Privacy Policy Consumer Health Data Privacy Policy
            • Policies and Notices
            Our Portfolio Plus Icon Minus Icon
            • Thermo Scientific
            • Applied Biosystems
            • Invitrogen
            • Gibco
            • Ion Torrent
            • Fisher Scientific
            • Unity Lab Services
            • Patheon
            • PPD
            • Terms & Conditions
            • Privacy Information Center
            • Price & Freight Policy
            • Cookie Preferences

              Your choices regarding cookies on this site

              We and our affiliates and vendors use cookies and similar technologies to operate our sites, recognize visitors to our sites, provide secure log-in, collect statistics to optimize site functionality, and deliver content tailored to your interests. Click Accept All to accept all cookies and go directly to the site, click Reject All to reject all but cookies strictly necessary to the functioning of this site (required cookies), or click on Manage Settings to see detailed descriptions of the types of cookies and choose whether to accept certain cookies while on the site.
            © 2006-2025 Thermo Fisher Scientific Inc. All rights reserved. All trademarks are the property of Thermo Fisher Scientific and its subsidiaries unless otherwise specified.
            united states flag icon
            United States

            Your items have has been added!


            Host server : magellan-search-blue-555ccb4fbd-glvc5:80/100.66.75.223:80.
            git-commit: 75f0c7d4cb44686da2af39b21f2e6446a20282e2
            git-url: https://github.com/thermofisher/magellan-search
            git-branch: release/2.41.0-2025.12.99-1.0