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Product Details
BS-3461R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic phosphopeptide derived from human PPIG around the phosphorylation site of Ser376 [VS (p-S)GE].
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregation defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CARS-cyclophilin; CARS-Cyp; CASP10; Clk-associating RS-cyclophilin; Cyclophilin G; Matrin cyclophilin; matrin cyclophilin (matrin-cyp); Matrin-cyp; MGC133241; OTTHUMP00000204761; OTTHUMP00000204762; Peptidyl-prolyl cis-trans isomerase G; peptidyl-prolyl isomerase G; peptidyl-prolyl isomerase G (cyclophilin G); peptidylprolyl isomerase G; peptidylprolyl isomerase G (cyclophilin G); PPIase G; Rotamase G; SR-cyclophilin; SR-cyp; SR-related CTD-associated factor 10
Gene Aliases: AU019516; AU022200; B230312B02Rik; CARS-Cyp; CYP; PPIG; SCAF10; SRCyp
UniProt ID: (Human) Q13427, (Rat) O55035, (Mouse) A2AR02
Entrez Gene ID: (Human) 9360, (Rat) 83624, (Mouse) 228005
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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