Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Phospho-beta-2 Adrenergic Receptor (Ser346) Polyclonal Antibody
Application
FIGURE: 1 / 2
Phospho-beta-2 Adrenergic Receptor (Ser346) Antibody (PA5-36784) in WB
Western blot analysis of Phospho-beta-2 Adrenergic Receptor (Ser346) in Lane 1: HepG2 cell lysate treated with PMA (100 nM,30mins), Lane 2: mouse spleen tissue lysate, Lane 3: rat spleen tissue lysate. Samples were incubated with Phospho-beta-2 Adrenergic Receptor (Ser346) polyclonal antibody (Product # PA5-36784) at a dilution of 1:500.
Product Details
PA5-36784
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic phosphopeptide derived from human AR-beta2 around the phosphorylation site of Serine 346
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2553730
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 47 kDa, 68 kDa (glycosylated) and 95 kDa (Dimer).
Purity is >95% by SDS-PAGE.
Target Information
Adrenergic receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines epinephrine and norepinephrine. Pharmacological, structural, and molecular cloning data indicate significant heterogeneity within this receptor family. Nine receptor subtypes have been identified thus far including three alpha-1 AR subtypes (1A/D, 1B, and 1C), three alpha-2 ARs (2A, 2B, and 2C), and three beta AR subtypes (1, 2, and 3). ARs participate in either the onset or maintenance of several disease states including hypertension, cardiac dysfunction (congestive heart failure, ischemia, arrhythmias), diabetes, glaucoma, depression, and impotence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Adrenergic beta 2- receptor surface; adrenergic receptor, beta 2; adrenergic, beta-2-, receptor, surface; adrenoceptor beta 2 surface; adrenoceptor beta 2, surface; AR beta2; beta 2-AR; Beta-2 adrenergic receptor; Beta-2 adrenoceptor; Beta-2 adrenoreceptor; beta2-Adrenoreceptor; catecholamine receptor; HGNC:286
Gene Aliases: Adrb-2; ADRB2; ADRB2R; ADRBR; B2AR; Badm; BAR; BETA2AR; Gpcr7
UniProt ID: (Human) P07550, (Mouse) P18762
Entrez Gene ID: (Human) 154, (Mouse) 11555, (Rat) 24176
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support