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Invitrogen
Procollagen I N-Peptide Monoclonal Antibody (C6)
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Application
FIGURE: 1 / 1
Procollagen I N-Peptide Antibody (MA5-41662) in WB
Western blot analysis of Procollagen I C-Peptide in recombinant human PINP. Sample was incubated with monoclonal antibody (Product # MA5-41662).
Product Details
MA5-41662
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C6
Immunogen
Recombinant protein Procollagen I N-Terminal Propeptide
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2899144
Target Information
Procollagen type I N-terminal propeptide (P1NP) is a specific marker of bone formation, reflecting the synthesis of type I collagen, which constitutes the major part of the bone matrix. P1NP is derived during the conversion of procollagen to collagen, produced by osteoblasts during bone formation. Its primary clinical application lies in the diagnosis and monitoring of metabolic bone diseases, particularly osteoporosis. In osteoporotic patients, P1NP levels can predict bone mineral density (BMD) responses to treatments like teriparatide and romosozumab. Low serum levels of P1NP are indicative of a high risk of BMD loss, providing a valuable tool for premenopausal women with systemic lupus erythematosus (SLE) and other conditions affecting bone health.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Alpha-1 type I collagen; alpha1(I) procollagen; collagen alpha 1 chain type I; Collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen of skin, tendon and bone, alpha-1 chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; P1NP; pro-alpha-1 collagen type 1; Procollagen I N; procollagen type I, alpha 1; procollagen, type 1, alpha 1; type I proalpha 1; type I procollagen alpha 1 chain; type I-alpha 1 collagen
Gene Aliases: COL1A1; COLIA1; EDSC; OI1; OI2; OI3; OI4
UniProt ID: (Human) P02452, (Rat) P02454
Entrez Gene ID: (Human) 1277, (Rat) 29393
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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