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Proteintech
Profilin 1 Monoclonal Antibody (3A12E8), CoraLite® Plus 488
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Product Details
CL488-67390
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
3A12E8
Immunogen
Profilin 1 fusion protein Ag29206
Conjugate
CoraLite® Plus 488
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAGWNAYID NLMADGTCQD AAIVGYKDSP SVWAAVPGKT FVNITPAEVG VLVGKDRSSF YVNGLTLGGQ KCSVIRDSLL QDGEFSMDLR TKSTGGAPTF NVTVTKTDKT LVLLMGKEGV HGGLINKKCY EMASHLRRSQ Y
Target Information
Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role in both signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but different expression patterns. Profilin I appears to be highly expressed in most tissues except for skeletal muscle. Profilin II is predominantly expressed in brain and at lower levels in skeletal muscle, uterus and kidney. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: actin binding protein; Epididymis tissue protein Li 184a; Profilin I; Profilin-1
Gene Aliases: ALS18; Pfn; PFN1
UniProt ID: (Human) P07737, (Rat) P62963, (Mouse) P62962
Entrez Gene ID: (Human) 5216, (Rat) 64303, (Mouse) 18643
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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