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Application
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Protein S Antibody (PA5-110737) in IHC (P)
Immunohistochemical analysis of Protein S in human testis using Protein S Polyclonal Antibody (Product # PA5-110737) using Anti-PROS1 antibody HPA007724.
Product Details
PA5-110737
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human Protein S. Recombinant protein control fragment (Product #RP-100455).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2856148
Product Specific Information
Immunogen sequence: QGASGIKEII QEKQNKHCLV TVEKGSYYPG SGIAQFHIDY NNVSSAEGWH VNVTLNIRPS TGTGVMLALV SGNNTVPFAV SLVDSTSEKS QDILLSVENT VIYRIQALSL CSDQQSHLEF RVNR
Target Information
Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 µg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma is in a free form, whereas 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Preproprotein S; PROS 1; Protein S alpha; protein Sa; proteinS; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS26; vitamin K-dependent plasma protein S; Vitamin K-dependent protein S
Gene Aliases: PROS; PROS1; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6
UniProt ID: (Human) P07225
Entrez Gene ID: (Human) 5627
platelet degranulation
signal peptide processing
ER to Golgi vesicle-mediated transport
blood coagulation
negative regulation of endopeptidase activity
peptidyl-glutamic acid carboxylation
regulation of complement activation
response to lipopolysaccharide
fibrinolysis
positive regulation of phagocytosis
leukocyte migration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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