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Immunogen sequence: KSCEVVSVCL PLNLDTKYEL LYLAEQFAGV VLYLKFRLPE ISRFSAEFDF RTYDSEGVIL YAESIDHSAW LLIALRGGKI EVQLKNEHTS KITTGGDVIN NGLWNMVSVE ELEHSISIKI AKEAVMDINK PGPLFKPENG LLETKV
Protein S is a vitamin K-dependent, potent neutral anticoagulant plasma glycoprotein. Protein S has a molecular weight of approximately 70 kDa and consists of a single polypeptide chain. The concentration of protein S in human plasma is 25 µg/mL, with a half-life of approximately two days. About 40% of Protein S in plasma is in a free form, whereas 60% is complexed with C4b-binding Protein (C4BP). Only the free Protein S functions as a cofactor to antigen presenting cells (APC) in the APC-dependent degradation of Factor Va and Factor VIIIa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Preproprotein S; PROS 1; Protein S alpha; protein Sa; proteinS; PS 21; PS 22; PS 23; PS 24; PS 25; PS 26; PS26; vitamin K-dependent plasma protein S; Vitamin K-dependent protein S
Gene Aliases: PROS; PROS1; PS21; PS22; PS23; PS24; PS25; PSA; THPH5; THPH6
UniProt ID: (Human) P07225
Entrez Gene ID: (Human) 5627
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