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Antibody detects endogenous levels of total RAB3GAP2.
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RAB3 GTPase activating protein subunit 2 (non-catalytic); Rab3 GTPase-activating protein 150 kDa subunit; Rab3 GTPase-activating protein non-catalytic subunit; Rab3-GAP p150; Rab3-GAP regulatory subunit; RAB3-GAP150; RGAP-iso
Gene Aliases: 1110059F07Rik; 2010002H18Rik; 5830469C09; AI851069; AW743433; KIAA0839; mKIAA0839; p150; RAB3-GAP150; RAB3GAP150; RAB3GAP2; RGD1311518; SPG69; WARBM2
UniProt ID: (Human) Q9H2M9, (Mouse) Q8BMG7, (Rat) Q5U1Z0
Entrez Gene ID: (Human) 25782, (Mouse) 98732, (Rat) 289350
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