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            Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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            • Primary Antibodies ›
            • RAMP1 Antibodies

            Alomone Labs, LTD

            RAMP1 (extracellular) Polyclonal Antibody

            View all (13) RAMP1 antibodies
            Datasheet
            Protocols
            Questions & Answers
            Datasheet
            Protocols
            Questions & Answers

            Cite RAMP1 (extracellular) Polyclonal Antibody

            • Antibody Testing Data (4)
            Application
            RAMP1 (extracellular) Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 4

            RAMP1 (extracellular) Antibody (ARR-021-200UL) in ICC/IF

            Expression of RAMP1 in rat PC12 cells - Cell surface detection of RAMP1 in intact living rat pheochromocytoma (PC12) cells. A. Extracellular staining of cells using Anti-RAMP1 (extracellular) Antibody (#ARR-021), (1:50), (red). B. Live view of cells.
            View Product

            RAMP1 (extracellular) Antibody in Immunocytochemistry (ICC/IF)
            RAMP1 (extracellular) Antibody in Immunohistochemistry (Frozen) (IHC (F))
            RAMP1 (extracellular) Antibody in Western Blot (WB)
            RAMP1 (extracellular) Antibody in Flow Cytometry (Flow)

            Product Details

            ARR-021-200UL

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:400
            -

            Immunohistochemistry (Frozen) (IHC (F))

            Assay-dependent
            -

            Immunocytochemistry (ICC/IF)

            1:50
            -

            Flow Cytometry (Flow)

            2.5 µg
            -
            Product Specifications

            Species Reactivity

            Mouse, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            CRDPDYGTLIQE, corresponding to amino acid residues 27-38 of rat RAMP1, Extracellular, N-terminus
            View immunogen

            Conjugate

            Unconjugated

            Form

            Lyophilized

            Concentration

            0.85 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.4, with 1% BSA

            Contains

            0.05% sodium azide

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Product Specific Information

            Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

            Target Information

            The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: MGC38240; receptor (calcitonin) activity modifying protein 1; Receptor activity-modifying protein 1

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            Gene Aliases: 9130218E19Rik; Ramp1

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            UniProt ID: (Rat) Q9JJ74, (Mouse) Q9WTJ5

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            Entrez Gene ID: (Rat) 58965, (Mouse) 51801

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            Function(s)

            G-protein coupled receptor binding receptor activity calcitonin receptor activity protein transporter activity coreceptor activity calcitonin receptor binding protein heterodimerization activity transmembrane signal receptor

            Process(es)

            angiogenesis calcium ion transport intracellular protein transport signal transduction G-protein coupled receptor signaling pathway regulation of G-protein coupled receptor protein signaling pathway protein transport positive regulation of cAMP biosynthetic process receptor internalization positive regulation of protein glycosylation protein localization to plasma membrane transport
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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