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产品信息
PA5-57247
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
形式
Liquid
浓度
0.10 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2646322
产品详细信息
Immunogen sequence: PDDYSNFVIE DSVTTFKTIQ QIKSIIEKLD EPHEKYRKKR SSSAKYGSKE NPIVGKAS
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
靶标信息
The Ras-related low molecular mass GTPases participate in signal transduction involving a variety of cellular functions, including cell-cycle progression, cellular differentiation, cytoskeletal organization, protein transport and secretion. The Ras-GTPase-activating protein (RASGAP) forms a complex with a second protein, p190, in growth factor stimulated and tyrosinekinase transformed cells. The RASGAP p190 complex may serve to couple Ras- and Rho-mediated signaling pathways. RASGAP forms an abundant SH2-mediated complex with p190 RhoGAP in cells expressing activated tyrosine kinases.
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生物信息学
蛋白别名: CM-AVM; CMAVM; DKFZp434N071; GAP; GAP1m; GTPase-activating protein 1m; GTPase-activating protein of RAS; p120GAP; p120RASGAP; PKWS; Ras GTPase-activating protein 2; RASA
基因别名: GAP1M; RASA2; RASGAP
UniProt ID: (Human) Q15283
Entrez Gene ID: (Human) 5922
