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Product Details
PA5-28857
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 403 and 621 of Human Ras GRF2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2546333
Product Specific Information
Recommended positive controls: mouse brain.
Predicted reactivity: Mouse (95%), Rat (94%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RAS (MIM 190020) GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. Guanine-nucleotide exchange factors (GEFs), such as RASGRFs, stimulate the conversion of the GDP-bound form into the active form.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ras guanine nucleotide exchange factor 2; Ras protein-specific guanine nucleotide-releasing factor 2; Ras-GRF2; Ras-specific guanine nucleotide-releasing factor 2
Gene Aliases: 6330417G04Rik; AW048350; GRF2; RAS-GRF2; RASGRF2
UniProt ID: (Human) O14827, (Mouse) P70392
Entrez Gene ID: (Human) 5924, (Mouse) 19418
MAPK cascade
small GTPase mediated signal transduction
regulation of Rho protein signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction
long-term synaptic potentiation
regulation of N-methyl-D-aspartate selective glutamate receptor activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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