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Invitrogen
RASGRP2 Polyclonal Antibody
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Application
FIGURE: 1 / 4
RASGRP2 Antibody (PA5-35111) in ICC/IF
Immunocytochemistry analysis of RASGRP2 in U-251MG cells. Samples were incubated in RASGRP2 polyclonal antibody (Product # PA5-35111) followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor555 phalloidin (red). DAPI was used to stain the cell nuclear (blue).
Product Details
PA5-35111
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human RASGRP2
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2552421
Product Specific Information
This antibody is predicted to react with bovine, mouse and rat based on sequence homology.
Target Information
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Calcium and DAG-regulated guanine nucleotide exchange factor I; calcium and diacylglycerol-regulated guanine nucleotide exchange factor I; CalDAG-GEFI; Cdc25-like protein; F25B3.3 kinase-like protein; guanine exchange factor MCG7; hCDC25L; RAS guanyl nucleotide-releasing protein 2; RAS guanyl releasing protein 2 (calcium and DAG-regulated); RAS guanyl-releasing protein 2
Gene Aliases: CALDAG-GEFI; CDC25L; MCG7; RASGRP2
UniProt ID: (Human) Q7LDG7
Entrez Gene ID: (Human) 10235
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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