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FIGURE: 1 / 1
RASSF2 Antibody (MA5-55545) in WB
Western Blot analysis of various lysates using RASSF2 Recombinant Monoclonal Antibody (Product # MA5-55545) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Product Details
MA5-55545
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
5U1E0
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 227-326 of human RASSF2.
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Dry ice (international)
Product Specific Information
Immunogen Sequence: HTSGEKQKLK ATDYPLIARI LQGPCEQISK VFLMEKDQVE EVTYDVAQYI KFEMPVLKSF IQKLQEEEDR EVKKLMRKYT VLRLMIRQRL EEIAETPATI
Target Information
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: centromere protein 34; Ras association (RalGDS/AF-6) domain family 2; Ras association (RalGDS/AF-6) domain family member 2; Ras association domain-containing protein 2; RP4-599I11.1
Gene Aliases: 3830431H01Rik; 9030412M04Rik; AI852669; AW495050; CENP-34; KIAA0168; RASFADIN; RASSF2
UniProt ID: (Human) A6NIX9, (Mouse) Q8BMS9, (Rat) Q3B7D5
Entrez Gene ID: (Human) 9770, (Mouse) 215653, (Rat) 311437
skeletal system development
ossification
protein phosphorylation
cell cycle
positive regulation of protein autophosphorylation
negative regulation of peptidyl-serine phosphorylation
epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade
positive regulation of apoptotic process
regulation of osteoblast differentiation
regulation of osteoclast differentiation
positive regulation of protein kinase activity
positive regulation of JNK cascade
bone remodeling
homeostasis of number of cells
protein stabilization
negative regulation of NIK/NF-kappaB signaling
signal transduction
regulation of NIK/NF-kappaB signaling
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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