Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody is tested in Peptide ELISA: antibody detection limit dilution 8,000.
Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HRAS1-related cluster protein 1; HRAS1-related cluster-1; MGC126069; MGC126070; Ras association (RalGDS/AF-6) domain family (N-terminal) member 7; Ras association (RalGDS/AF-6) domain family 7; Ras association domain-containing protein 7
Gene Aliases: C11orf13; HRAS1; HRC1; RASSF7
UniProt ID: (Human) Q02833
Entrez Gene ID: (Human) 8045
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