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Antibody detects endogenous levels of total hnRNP G.
hnRNP G is a glycoprotein, which was originally identified as an autoantigen from German shepherd dogs with lupus-like syndrome. The gene encoding hnRNP G is located on chromosome Xq26 and is ubiquitously expressed. It contains one RNP-consensus RNA binding domain (RBD) and is related to RBMY, which is involved in spermatogenesis, and hnRNP G-T, which is a testis specific protein. All three proteins interact with Tra2b and therefore, are involved in pre-mRNA splicing.
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Protein Aliases: Glycoprotein p43; Heterogeneous nuclear ribonucleoprotein G; hnRNP G; RNA binding motif protein, X chromosome; RNA-binding motif protein, X chromosome; RNA-binding motif protein, X chromosome retrogene; RNA-binding motif protein, X chromosome retrogene-like
Gene Aliases: hnRNP G; hnRNP-G; HNRNPG; HNRPG; MRXS11; RBMX; RBMXP1; RBMXRT; RNMX
UniProt ID: (Human) P38159, (Mouse) Q9WV02, (Rat) Q4V898
Entrez Gene ID: (Human) 27316, (Mouse) 19655, (Rat) 302855
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