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Product Details
17008-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RECQL4 Fusion Protein Ag10707 (297-652 aa encoded by BC013277)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This is a rabbit polyclonal antibody raised against part of C-terminal of RECQ4 of human origin. The calculated molecular weight of EIF3B is 133 kDa, but the modified EIF3B protein is about 145-150 kDa.
Immunogen sequence: CTCTCTRPP SEQEGAVGGE RPVPKYPPQE AEQLSHQAAP GPRRVCMGHE RALPIQLTVQ ALDMPEEAIE TLLCYLELHP HHWLELLATT YTHCRLNCPG GPAQLQALAH RCPPLAVCLA QQLPEDPGQG SSSVEFDMVK LVDSMGWELA SVRRALCQLQ WDHEPRTGVR RGTGVLVEFS ELAFHLRSPG DLTAEEKDQI CDFLYGRVQA RERQALARLR RTFQAFHSVA FPSCGPCLEQ QDEERSTRLK DLLGRYFEEE EGQEPGGMED AQGPEPGQAR LQDWEDQVRC DIRQFLSLRP EEKFSSRAVA RIFHGIGSPC YPAQVYGQDR RFWRKYLHLS FHALVGLATE ELLQVAR (297-652 aa encoded by BC013277 )
Target Information
The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ATP-dependent DNA helicase Q4; DNA 3'-5' helicase RecQ4; DNA helicase, RecQ-like type 4; DNA helicase, RecQ-like, type 4; RecQ helicase-like 4; RecQ protein-like 4; RecQ4; RTS
Gene Aliases: RECQ4; RECQL4
UniProt ID: (Human) O94761
Entrez Gene ID: (Human) 9401
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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