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REEP5 Antibody (PA5-106289) in IHC (P)
Immunohistochemistry analysis of REEP5 in human lung cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with REEP5 polyclonal antibody (Product # PA5-106289) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-106289
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human REEP5(Accession Q00765), corresponding to amino acid residues M1-L49.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853966
Product Specific Information
Antibody detects endogenous levels of total REEP5.
Target Information
REEP5 (receptor expression-enhancing protein 5), also known as C5orf18, DP1, TB2 or D5S346, is a 189 amino acid multi-pass membrane protein. Thought to promote the functional cell surface expression of olfactory receptors, REEP5 belongs to the DP1 family and is encoded by a gene that maps to chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the parm of chromosome 5 leads to cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: deleted in polyposis 1; GP106; polyposis coli region hypothetical protein DP1; Polyposis locus protein 1; Polyposis locus protein 1 homolog; Protein TB2; protein TB2 homolog; receptor expression enhancing protein 5; Receptor expression-enhancing protein 5
Gene Aliases: AI324241; AU022809; AW495741; C5orf18; D5S346; DP1; DP1/TB2; R74856; REEP5; TB2; TB2/DP1; Yip2e; YOP1
UniProt ID: (Human) Q00765, (Rat) B2RZ37
Entrez Gene ID: (Human) 7905, (Rat) 364838, (Mouse) 13476
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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