Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
12549-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RGS17 Fusion Protein Ag3399 (1-210 aa encoded by BC013117)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.43 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MRKRQQSQN EGTPAVSQAP GNQRPNNTCC FCWCCCCSCS CLTVRNEERG ENAGRPTHTT KMESIQVLEE CQNPTAEEVL SWSQNFDKMM KAPAGRNLFR EFLRTEYSEE NLLFWLACED LKKEQNKKVI EEKARMIYED YISILSPKEV SLDSRVREVI NRNLLDPNPH MYEDAQLQIY TLMHRDSFPR FLNSQIYKSF VESTAGSSSE S (1-210 aa encoded by BC013117)
Target Information
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Regulator of G-protein signaling 17; regulator of G-protein signaling Z2; Regulator of Gz-selective protein signaling 2; RGS17
Gene Aliases: 6430507P11Rik; hRGS17; RGS-17; RGS17; RGSZ2
UniProt ID: (Human) Q9UGC6, (Mouse) Q9QZB0
Entrez Gene ID: (Human) 26575, (Mouse) 56533
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support