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            • Primary Antibodies ›
            • RING1 Antibodies

            Invitrogen

            RING1 Polyclonal Antibody

            View all (30) RING1 antibodies

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            Datasheet
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            Catalog # PA5-82361
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            Price (USD)
            498.00
            100 µL
             
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            Cite RING1 Polyclonal Antibody

            • Antibody Testing Data (5)
            Application
            RING1 Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 5

            RING1 Antibody (PA5-82361) in ICC/IF

            Immunofluorecent analysis of RING1 in human cell line A-431 using RING1 Polyclonal Antibody (Product # PA5-82361). Staining shows localization to nucleoplasm and cytosol.
            View Product

            RING1 Antibody in Immunocytochemistry (ICC/IF)
            RING1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            RING1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            RING1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            RING1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

            Product Details

            PA5-82361

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            0.04-0.4 µg/mL
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:200-1:500
            -

            Immunocytochemistry (ICC/IF)

            0.25-2 µg/mL
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant protein corresponding to Human RING1. Recombinant protein control fragment (Product #RP-89328).
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.05 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.2, with 40% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2789520

            Product Specific Information

            Immunogen sequence: TRYVKTTGNA TVDHLSKYLA LRIALERRQQ QEAGEPGGPG GGASDTGGPD GCGGEGGGAG GGDGPEEPAL PSLEGVSEKQ YTIYIAPGGG AFTTLNGSLT LELVNEKFWK VS

            Target Information

            This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: E3 ubiquitin-protein ligase RING1; Polycomb complex protein RING1; Really interesting new gene 1 protein; RING finger protein 1; RING-type E3 ubiquitin transferase RING1

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            Gene Aliases: RING1; RING1A; RNF1

            View more View less

            UniProt ID: (Human) Q06587

            View more View less

            Entrez Gene ID: (Human) 6015

            View more View less

            Function(s)

            chromatin binding protein binding zinc ion binding ligase activity ubiquitin-protein transferase activator activity ubiquitin-protein ligase

            Process(es)

            transcription, DNA-templated anterior/posterior pattern specification protein sumoylation histone H2A monoubiquitination negative regulation of transcription, DNA-templated camera-type eye morphogenesis regulation of catalytic activity
            It has to be done as per old AB suggested Products section.
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