Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Sequence of this protein is as follows: MKTSCSHGSS DYHTRFATVN ILPEVENDRL ENSPHQCSIS VVTQTASCSE VSQLNHIAEE HGNNGIKPNV DLYFGDALKE TNNNHSHQTM ELKVAIQTE
This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dorfin; Double ring-finger protein; E3 ubiquitin-protein ligase RNF19A; p38; protein p38 interacting with transcription factor Sp1; ring finger protein 19; RING finger protein 19A; ring finger protein 19A, E3 ubiquitin protein ligase; ring-IBR-ring domain containing protein Dorfin
Gene Aliases: RNF19; RNF19A
UniProt ID: (Human) Q9NV58
Entrez Gene ID: (Human) 25897
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn moreGet expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support