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Immunogen sequence: LALALPGSL DEALEEGLVT ALAHYKDTEV PGHCQAKRLV DELQLRYHCC GRHGYKDWFG VQWVSSRYLD PGDRDVADRI QSNVEGLYLT DGVPFSCCNP HSPRPCLQNR LSDSYAHPLF DPRQPNQNLW AQGCHEVLLE HLQDLAGTLG S (121-270 aa encoded by BC008100)
This gene is a member of a photoreceptor-specific gene family and encodes an integral membrane protein found in the photoreceptor disk rim of the eye. This protein can form homodimers or can heterodimerize with another photoreceptor, retinal degeneration slow (RDS). It is essential for disk morphogenesis, and may also function as an adhesion molecule involved in the stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Certain defects in this gene have been associated with the degenerative eye disease retinitis pigmentosa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Rod outer segment membrane protein 1; ROSP1; Tetraspanin-23; Tspan-23
Gene Aliases: M101156; Rgsc1156; ROM; Rom-1; ROM1; ROSP1; RP7; TSPAN23
UniProt ID: (Human) Q03395, (Rat) Q5PPM7, (Mouse) P32958
Entrez Gene ID: (Human) 6094, (Rat) 309201, (Mouse) 19881
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