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Immunogen sequence: MADTIFGSG NDQWVCPNDR QLALRAKLQT GWSVHTYQTE KQRRKQHLSP AEVEAILQVI QRAERLDVLE QQRIGRLVER LETMRQNVMG NGLSQCLLCG EVLGFLGSSS VFCKDCRKVW KRSGAWFYKG LPKYILPLKT PGRADDPHFR PLPTEPAERE PRSSETSRIY TWARGRVVSS DSDSDSDLSS SSLEDRLPST GVRDRKGDKP WKESGGSVEA PRMGFTHPPG HLSGCQSSLA SGETGTGSAD PPGGPRPGLT RRAPVKDTPG RAPAADAAPA GPSSCLG (1-286 aa encoded by BC005153)
The protein encoded by this gene plays a direct regulatory role in calcium-ion-dependent exocytosis in both endocrine and exocrine cells and plays a key role in insulin secretion by pancreatic cells. This gene is likely a tumor suppressor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: No C2 domains protein; Rab effector Noc2; Rabphilin-3A-like protein
Gene Aliases: NOC2; RPH3AL
UniProt ID: (Human) Q9UNE2
Entrez Gene ID: (Human) 9501
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