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Immunogen sequence: MENFRKVRSE EAPAGCGAEG GGPGSGPFAD LAPGAVHMRV KEGSKIRNLM AFATASMAQP ATRAIVFSGC GRATTKTVTC AEILKRRLAG LHQVTRLRYR SVREVWQSLP PGPTQGQTPG EPAASLSVLK NVPGLAILLS KDALDPRQPG YQPPNPHPGP SSPPAAPASK RSLGEPAAGE GSAKRSQPEP GVADEDQTA; Positive Samples: A-375, HeLa, HT-29; Cellular Location: Nucleus
Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends (PubMed:12003489, PubMed:16723659, PubMed:30454648). Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences (PubMed:28115465). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ribonuclease P 25 subunit; ribonuclease P 25kDa subunit; Ribonuclease P protein subunit p25; ribonuclease P/MRP 25kDa subunit; RNase P protein subunit p25
Gene Aliases: AI851155; RPP25
UniProt ID: (Human) Q9BUL9, (Mouse) Q91WE3
Entrez Gene ID: (Human) 54913, (Mouse) 102614
Molecular Function:
endoribonuclease
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