Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: NVIISSAAER PLEIRGPYDV ANLGLLFGLS ESDAKAAVST NCRAALLHGE TRKTAFGIIS TVKKPRPSEG DEDCLPASKK AKCEG
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 85%.
RNase P, which consists of a complex of an RNA species (H1 RNA), POP1 (Processing of Precursor 1), POP5 (Processing of Precursor 5), and at least seven Rpps (including Rpp14, Rpp29, Rpp30 and Rpp38), removes the 5' leader sequences from precursor tRNA molecules. The structurally related RNase MRP plays an essential role in the formation of the 5' end of 5.8S rRNA. Both RNase P and RNase MRP are associated with Th/To ribonucleoproteins; Rpp30 and Rpp38 have specifically been implicated as Th autoantigens which contribute to the autoimmune disease systemic sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ribonuclease P protein subunit p30; ribonuclease P/MRP 30kDa subunit; RNase P subunit 2; RNaseP protein p30
Gene Aliases: RNASEP2; RPP30; TSG15
UniProt ID: (Human) P78346
Entrez Gene ID: (Human) 10556
Molecular Function:
endoribonuclease
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