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Application
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RPS17 Antibody (PA5-103533) in WB
Western blot analysis of RPS17 in mouse testis tissue lysate (left lane: treated with blocking peptide). Samples were incubated with RPS17 polyclonal antibody (Product # PA5-103533).
Product Details
PA5-103533
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RPS17(Accession P08708), corresponding to amino acid residues Y21-I71.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2852869
Product Specific Information
Antibody detects endogenous levels of total RPS17.
Target Information
Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein S17, also known as RPS17, RPS17L1 or RPS17L2, is a 135 amino acid protein that is a component of the 40S subunit. Localized to the cytoplasm and expressed ubiquitously, Ribosomal Protein S17 belongs to the S17e family of ribosomal proteins and functions in protein synthesis. Mutations in the gene encoding Ribosomal Protein S17 are associated with Diamond-Blackfan anemia (DBA), a rare congenital disorder characterized by defective differentiation of pro-erythroblasts. Like most ribosomal proteins, Ribosomal Protein S17 exists as multiple processed pseudogenes that are scattered throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 40S ribosomal protein S17; Small ribosomal subunit protein eS17
Gene Aliases: DBA4; RPS17; RPS17L; RPS17L1; RPS17L2; S17
UniProt ID: (Human) P08708, (Mouse) P63276, (Rat) P04644
Entrez Gene ID: (Human) 6218, (Mouse) 20068, (Rat) 29286
ribosomal small subunit assembly
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
rRNA processing
translation
translational initiation
SRP-dependent cotranslational protein targeting to membrane
viral transcription
erythrocyte homeostasis
ribosomal small subunit biogenesis
translational elongation
biological_process
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