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Positive test controls include: Mouse testis. The target is usually found in the following locations: Secreted.
Immunogen sequence: DMNKCIKCKI EHCEACFSHN FCTKCKEGLY LHKGRCYPAC PEGSSAANGT MECSSPAQCE MSEWSPWGPC SKKQQLCGFR RGSEERTRRV LHAPVGDHAA CSDTKETRRC TVRRVPCPEG Q
This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cristin-3; Cysteine-rich and single thrombospondin domain-containing protein 3; FLJ40906; hRspo1; mCristin-3; R-spondin homolog; R-spondin-1; Roof plate-specific spondin-1; RP11-566C13.1; thrombospondin type 1 domain containing gene Rspondin
Gene Aliases: CRISTIN3; R-spondin; RGD1565558; RSPO; RSPO1; Rspondin
UniProt ID: (Human) Q2MKA7, (Mouse) Q9Z132
Entrez Gene ID: (Human) 284654, (Rat) 313589, (Mouse) 192199
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