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Invitrogen

RXRB Polyclonal Antibody

View all (16) RXRB antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (1)

Application

RXRB Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 1

RXRB Antibody (PA5-145086) in ICC/IF

Immunocytochemistry analysis of RXRB in U2OS cells. Samples were incubated with RXRB polyclonal antibody (Product # PA5-145086). Shows localization to nucleoplasm, nucleoli & cytosol.

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Product Details

PA5-145086

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 1-46. Recombinant protein control fragment (Product #RP-110024).

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Conjugate

Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_3091841

Product Specific Information

Immunogen sequence: MSWAARPPFL PQRHAAGQCG PVGVRKEMHC GVASRWRRRR PWLDPA

Antigen sequence identity: Mouse 96%; Rat 96%

Target Information

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA). This receptor forms homodimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. The gene lies within the major histocompatibility complex (MHC) class II region on chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DADB-100D22.1; MGC1831; MHC class I promoter binding protein; Nuclear receptor subfamily 2 group B member 2; Retinoic acid receptor RXR-beta; retinoid X receptor; Retinoid X receptor beta; retinoid X receptor, beta; RXR Beta

Gene Aliases: DAUDI6; H-2RIIBP; NR2B2; RCoR-1; RXRB

UniProt ID: (Human) P28702

Entrez Gene ID: (Human) 6257

Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity transcription coactivator activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding 9-cis retinoic acid receptor activity protein binding zinc ion binding thyroid hormone receptor coactivator activity vitamin D receptor binding retinoic acid receptor binding thyroid hormone receptor binding protein heterodimerization activity C4 zinc finger nuclear receptor

Process(es)

transcription initiation from RNA polymerase II promoter regulation of myelination steroid hormone mediated signaling pathway positive regulation of transcription from RNA polymerase II promoter retinoic acid receptor signaling pathway positive regulation of receptor activity

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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