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产品信息
500-10054
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the C-terminus human Rho protein
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with proprietary stabilizer
内含物
0.01% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive control: MCF7 Cell Lysate
Cellular location: Cell membrane, Cytoplasm.
靶标信息
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Aplysia ras-related homolog 12; Aplysia RAS-related homolog 6; aplysia ras-related homolog 9 (RhoC); aplysia ras-related homolog A; aplysia ras-related homolog A1; aplysia ras-related homolog A2; aplysia ras-related homolog B; epididymis secretory protein Li 42; h12; h6; h9; induced in fatty liver dystrophy 1; oncogene RHO H12; oncogene RHO H6; oncogene RHO H9; plysia ras-related homolog A2; Ras family member A; ras homolog 9 (RhoC); ras homolog A1; ras homolog A2; ras homolog B; ras homolog family member F (in filopodia); ras homolog gene family, member A; ras homolog gene family, member A1; ras homolog gene family, member A2; ras homolog gene family, member AB; ras homolog gene family, member B; ras homolog gene family, member C; ras homolog gene family, member F (in filopodia); ras homolog gene family, member Q; Ras-like protein family member 7A; Ras-like protein TC10; RAS-like, family 7, member A; ras-related GTP-binding protein TC10; RAS-related homolog 9; Rho cDNA clone 12; Rho cDNA clone 6; Rho cDNA clone 9; rho family; Rho family GTPase; Rho family GTPase Rif; Rho in filopodia; Rho-related GTP-binding protein RhoB; Rho-related GTP-binding protein RhoC; Rho-related GTP-binding protein RhoF; Rho-related GTP-binding protein RhoQ; rhoB; rhoC GTPase; SIG-61; Silica-induced gene 61 protein; small GTP binding protein RhoA; small GTP binding protein RhoC; small GTPase Tc10; Transforming protein RhoA
基因别名: AA017882; AI324259; AI845056; ARH12; ARH6; ARH9; ARHA; Arha1; Arha2; ARHB; ARHC; ARHF; ARHQ; AV026554; H9; HEL-S-42; Ifld1; MST081; MSTP081; RASL7A; RHO12; RHOA; RHOB; RHOC; RHOF; RHOH12; RHOH6; RHOH9; RHOQ; RIF; TC10; TC10A
