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The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer.
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Protein Aliases: CAN19; Protein S-100L; Protein S100-A2; S100 calcium-binding protein A2
Gene Aliases: CAN19; S100A2; S100L
UniProt ID: (Human) P29034
Entrez Gene ID: (Human) 6273
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