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            • Primary Antibodies ›
            • SAM68 Antibodies

            Bioss

            SAM68 Polyclonal Antibody

            View all (17) SAM68 antibodies
            Datasheet
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            Catalog # BS-13699R
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            Price (USD)
            444.00
            100 µL
             
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            Cite SAM68 Polyclonal Antibody

            • Antibody Testing Data (1)
            Application
            SAM68 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            SAM68 Antibody (BS-13699R) in IHC (P)

            Paraformaldehyde-fixed, paraffin embedded Rat brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with SAM68 Polyclonal Antibody, Unconjugated (bs-13699R) at 1:200 overnight at 4°C, DAB staining.
            View Product

            SAM68 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

            Product Details

            BS-13699R

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:300-1:1,000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:200
            -

            Immunohistochemistry (Frozen) (IHC (F))

            1:100-1:500
            -

            Immunocytochemistry (ICC/IF)

            1:100-1:500
            -

            ELISA (ELISA)

            1:500-1:1,000
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            KLH conjugated synthetic peptide derived from human SAM68, amino acids 101-200.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Protein A

            Storage buffer

            0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

            Contains

            0.02% ProClin 300

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Cite this product

            Bioinformatics

            Protein Aliases: FLJ34027; GAP-associated tyrosine phosphoprotein p62; GAP-associated tyrosine phosphoprotein p62 (Sam68); KH domain containing, RNA binding, signal transduction associated 1; KH domain-containing, RNA-binding, signal transduction-associated protein 1; KHDRBS1; khdrbs1 {ECO:0000312|RGD:621459}; p21 Ras GTPase-activating protein-associated p62; p68; Sam68; src associated in mitosis, 68 kDa; Src-associated in mitosis 68 kDa protein

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            Gene Aliases: KHDRBS1; P62; p68; SAM68

            View more View less

            UniProt ID: (Human) Q07666, (Mouse) Q60749, (Rat) Q91V33

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            Entrez Gene ID: (Human) 10657, (Mouse) 20218, (Rat) 117268

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            Function(s)

            DNA binding RNA binding SH3/SH2 adaptor activity protein binding poly(A) binding poly(U) RNA binding SH3 domain binding protein complex binding identical protein binding poly(A) RNA binding nucleic acid binding RNA splicing factor

            Process(es)

            G2/M transition of mitotic cell cycle transcription, DNA-templated mRNA processing cell cycle arrest signal transduction cell surface receptor signaling pathway cell proliferation positive regulation of signal transduction regulation of protein stability negative regulation of transcription, DNA-templated positive regulation of translational initiation regulation of RNA export from nucleus positive regulation of RNA export from nucleus regulation of transcription, DNA-templated cell cycle regulation of signal transduction
            It has to be done as per old AB suggested Products section.
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