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Product Details
IHC-00578
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 1 and 50 of Human Src-associated in mitosis 68 kDa protein (KH domain containing, RNA binding, signal transduction associated 1).
Conjugate
Form
Liquid
Concentration
50 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
TBS, pH 7.0 to 8.0, with 0.1% BSA
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Rabbit, Guinea pig_10141, Orangutan, Monkey, Gorilla, Chimpanzee, Small-eared galago and Crab-eating macaque
Target Information
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ34027; GAP-associated tyrosine phosphoprotein p62; GAP-associated tyrosine phosphoprotein p62 (Sam68); KH domain containing, RNA binding, signal transduction associated 1; KH domain-containing, RNA-binding, signal transduction-associated protein 1; KHDRBS1; p21 Ras GTPase-activating protein-associated p62; p68; Sam68; src associated in mitosis, 68 kDa; Src-associated in mitosis 68 kDa protein
Gene Aliases: KHDRBS1; p62; p68; SAM68
UniProt ID: (Human) Q07666, (Mouse) Q60749
Entrez Gene ID: (Human) 10657, (Mouse) 20218
G2/M transition of mitotic cell cycle
transcription, DNA-templated
mRNA processing
cell cycle arrest
signal transduction
cell surface receptor signaling pathway
cell proliferation
positive regulation of signal transduction
regulation of protein stability
negative regulation of transcription, DNA-templated
positive regulation of translational initiation
regulation of RNA export from nucleus
positive regulation of RNA export from nucleus
regulation of transcription, DNA-templated
cell cycle
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