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Product Details
CF504668
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Human,
Rat
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
OTI2B7
Immunogen
Full length human recombinant protein of human SCFD1 produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Sec1 family domain-containing protein 1; SLY1 homolog; Sly1p; Syntaxin-binding protein 1-like 2; vesicle transport-related protein; Vesicle transport-related protein Ra410
Gene Aliases: C14orf163; FKSG23; KIAA0917; RA410; rSly1; SCFD1; SLY1; SLY1P; STXBP1L2
UniProt ID: (Human) Q8WVM8, (Rat) Q62991
Entrez Gene ID: (Dog) 480281, (Human) 23256, (Rat) 54350
cell morphogenesis
response to hypoxia
retrograde vesicle-mediated transport, Golgi to ER
post-Golgi vesicle-mediated transport
vesicle docking involved in exocytosis
phagocytosis
response to toxic substance
protein transport
COPII vesicle coating
regulation of protein transport
regulation of ER to Golgi vesicle-mediated transport
toxin transport
negative regulation of autophagosome assembly
ER to Golgi vesicle-mediated transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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