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Immunogen sequence: DMRNYAKRKG WWDGKKEFDF AAAYSYLDTA KMMTSSGRYC EGYKLLNKHK GNITFETMME ILRDKPSGIN MEGEFLTTA
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.
SCRN3 is a member of the secernin family of proteins which includes the homologous SCRN1, a protein that was first identified as being involved in the regulation of exocytosis from peritoneal mast cells. Little is known of SCRN3, but studies have shown that SCRN1 may possess epitopes that function as tumor-associated antigens in gastric cancers and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN3 may also be involved in protein secretion or the regulation of cell growth.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Secernin-3
Gene Aliases: SCRN3; SES3
UniProt ID: (Human) Q0VDG4
Entrez Gene ID: (Human) 79634
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