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Application
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SDHAF3 Antibody (PA5-24526) in IHC (P)
Immunohistochemistry analysis of ACN9 in formalin fixed and paraffin embedded human hepatocarcinoma. Samples were incubated with ACN9 polyclonal antibody (Product # PA5-24526) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-24526
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human ACN9
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542026
Target Information
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ACN9 homolog; protein ACN9 homolog, mitochondrial; SDH assembly factor 3; Succinate dehydrogenase assembly factor 3, mitochondrial
Gene Aliases: 0610005M07Rik; 4933430A16Rik; ACN9; DC11; LYRM10; Sdh7; SDHAF3
UniProt ID: (Human) Q9NRP4, (Mouse) Q8BQU3
Entrez Gene ID: (Human) 57001, (Mouse) 71238
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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