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Positive test controls include: SGC-7901, HT-29, Raji, HepG2, A-549, Mouse kidney, Mouse liver, Mouse lung, Rat brain. The target is usually found in the following locations: Endoplasmic reticulum membrane, Microsome membrane, Single-pass type II membrane protein.
Immunogen sequence: KGLMVITGSE SPIVVVLSGS MEPAFHRGDL LFLTNRVEDP IRVGEIVVFR IEGREIPIVH RVLKIHEKQN GHIKFLTKGD NNAVDDRGLY KQGQHWLEKK DVVGRARGF
This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Endopeptidase SP18; Microsomal signal peptidase 18 kDa subunit; SEC11 homolog A; Sec11-like 1; SEC11-like protein 1; Sid 2895; signal peptidase complex (18kD); signal peptidase complex 18; signal peptidase complex 18kD; Signal peptidase complex catalytic subunit SEC11A; SPase 18 kDa subunit; SPC18
基因别名: 1810012E07Rik; 18kDa; SEC11A; SEC11L1; Sid2895; Sid2895p; SPC18; SPCS4A
UniProt ID: (Human) P67812, (Mouse) Q9R0P6
Entrez Gene ID: (Human) 23478, (Mouse) 56529, (Rat) 65166