Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: TWSVEKVIQV PPKKVKGWLL PEMPGLITDI LLSLDDRFLY FSNWLHGDLR QYDISDPQRP RLTGQLFLGG SIVKGGPVQV LEDEELKSQP EPLVVKGKRV AGGPQMIQLS LDGKRLYITT SLYSAWDKQF YPDLI
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 90%.
Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 56 kDa selenium-binding protein; epididymis secretory sperm binding protein Li 134P; FLJ13813; hSP56; Lp 56; Methanethiol oxidase; MTO; SBP 1; SBP56; Selen bp2; SELENBP 1; Selenbp 2; Selenium-binding protein 1; SELNBP1; SP 56
Gene Aliases: HEL-S-134P; hSBP; LPSB; SBP; SBP56; SELENBP1; SP56
UniProt ID: (Human) Q13228
Entrez Gene ID: (Human) 8991
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