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Product Details
BS-11479R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human SEMA4G, amino acids 71-120.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The SEMA4G gene encodes semaphorin 4G, a member of the semaphorin protein family known for their roles in cellular guidance, signaling, and development. Semaphorin 4G is involved in axonal guidance, where it influences the direction and growth of neurons by interacting with receptor complexes such as plexins. This interaction is critical in neural development, contributing to the proper formation of neural circuits by ensuring that neurons connect accurately and functionally. Beyond its role in the nervous system, SEMA4G also participates in immune responses, where it modulates the activity and migration of immune cells, influencing processes like inflammation and immune surveillance. This protein's modulation of cell-to-cell communication and migration extends to its implications in cancer, where altered semaphorin signaling can impact tumor progression and metastasis through changes in cell adhesion and migration properties. Research into SEMA4G continues to investigate its precise mechanisms and interactions, providing insights into therapeutic opportunities in neural disorders and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KIAA1619FLJ20590; MGC102867; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G; Semaphorin-4G
Gene Aliases: AI507908; AW554132; KIAA1619; SEMA4G
UniProt ID: (Human) Q9NTN9, (Mouse) Q9WUH7
Entrez Gene ID: (Human) 57715, (Mouse) 26456, (Rat) 361764
Performance Guarantee
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