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Abnova
SEMA4G Monoclonal Antibody (3F2)
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Product Details
H00057715-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
3F2
Immunogen
SEMA4G (NP_060363, 24 a.a. approximately 115 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: RRPSRELDAT PRMTIPYEEL SGTRHFKGQA QNYSTLLLEE ASARLLVGAR GALFSLSAND IGDGAHKEIH WEASPEMQSK CHQKGKNNQT EC
Target Information
The SEMA4G gene encodes semaphorin 4G, a member of the semaphorin protein family known for their roles in cellular guidance, signaling, and development. Semaphorin 4G is involved in axonal guidance, where it influences the direction and growth of neurons by interacting with receptor complexes such as plexins. This interaction is critical in neural development, contributing to the proper formation of neural circuits by ensuring that neurons connect accurately and functionally. Beyond its role in the nervous system, SEMA4G also participates in immune responses, where it modulates the activity and migration of immune cells, influencing processes like inflammation and immune surveillance. This protein's modulation of cell-to-cell communication and migration extends to its implications in cancer, where altered semaphorin signaling can impact tumor progression and metastasis through changes in cell adhesion and migration properties. Research into SEMA4G continues to investigate its precise mechanisms and interactions, providing insights into therapeutic opportunities in neural disorders and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: KIAA1619FLJ20590; MGC102867; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G; Semaphorin-4G
Gene Aliases: KIAA1619; SEMA4G
UniProt ID: (Human) Q9NTN9
Entrez Gene ID: (Human) 57715
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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