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MA5-17647 targets PI-8/Proteinase Inhibitor 8 in ELISA and WB applications and shows reactivity with Human samples.
The MA5-17647 immunogen is human Proteinase Inhibitor 8 (PI8) purified from the supernatant of thrombin activated platelets.
The superfamily of high molecular weight serine proteinase inhibitors. A critical portion of the molecule, the reactive center loop connects beta sheets A and C. Protease inhibitor-8 (PI8; SERPINB8) is a member of the ov-serpin subfamily, which, relative to the archetypal serpin PI1 (MIM 107400), is characterized by a high degree of homology to chicken ovalbumin, lack of N- and C-terminal extensions, absence of a signal peptide, and a serine rather than an asparagine residue at the penultimate position.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CAP-2; Cytoplasmic antiproteinase 2; Peptidase inhibitor 8; PI-8; protease inhibitor 8 (ovalbumin type); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 8; Serpin B8; serpin peptidase inhibitor, clade B (ovalbumin), member 8
Gene Aliases: CAP2; PI8; SERPINB8
UniProt ID: (Human) P50452
Entrez Gene ID: (Human) 5271
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