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Sequence of this protein is as follows: KNTSSDSLTK FNKGNVFLLD ATKEGNVGRF LNHSCCPNLL VQNVFVETHN RNFPLVAFFT NRYVKARTEL TWDYGYEAGT VPEKEIFCQC GVNKCRKKIL
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bifurcated 2; Chronic lymphocytic leukemia deletion region gene 8 protein; CLLL8 protein; DKFZp586I0123; DKFZp761J1217; Histone-lysine N-methyltransferase SETDB2; Lysine N-methyltransferase 1F; SET domain; SET domain bifurcated 2
Gene Aliases: C13orf4; CLLD8; CLLL8; KMT1F; SETDB2
UniProt ID: (Human) Q96T68
Entrez Gene ID: (Human) 83852
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