Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
SF3B5 is a protein coding gene involved in pre-mRNA splicing as a component of the splicing factor SF3B complex, a constituent of the spliceosome. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.
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Protein Aliases: MGC3133; Pre-mRNA-splicing factor SF3b 10 kDa subunit; SF3b5; Splicing factor 3B subunit 5
Gene Aliases: 10kDa; 1110005L13Rik; AU043053; Sf3b10; Sf3b5
UniProt ID: (Mouse) Q923D4
Entrez Gene ID: (Mouse) 66125
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