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            • Primary Antibodies ›
            • SFRS8 Antibodies

            Proteintech

            SFRS8 Polyclonal Antibody

            2 References
            View all (8) SFRS8 antibodies
            Datasheet
            Protocols
            Questions & Answers
            Catalog # 24705-1-AP
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            Price (USD)
            492.00
            150 µL
             
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            Datasheet
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            Cite SFRS8 Polyclonal Antibody

            • Antibody Testing Data (3)
            Application
            SFRS8 Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 3

            SFRS8 Antibody (24705-1-AP) in ICC/IF

            Immunofluorescent analysis of HeLa cells using 24705-1-AP (SFRS8 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).
            View Product

            SFRS8 Antibody in Immunocytochemistry (ICC/IF)
            SFRS8 Antibody in Western Blot (WB)
            SFRS8 Antibody in Western Blot (WB)

            Product Details

            24705-1-AP

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:1,000-1:4,000
            View 1 publication 1 publication

            Immunohistochemistry (IHC)

            -
            View 1 publication 1 publication

            Immunocytochemistry (ICC/IF)

            1:20-1:200
            -
            Product Specifications

            Species Reactivity

            Human

            Published species

            Human, Mouse

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            SFRS8 Fusion Protein Ag19762 (600-951 aa encoded by BC136678)
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.4 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.3, with 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C

            Shipping conditions

            Wet ice (domestic); Dry ice (international)

            Product Specific Information

            This antibody detects 130-150 kDa SFRS8 protein.

            Immunogen sequence: LDDDSDDDE ESKEGQESSS SAANTNPAVA PPCVVVEEKK PQLTQEELEA KQAKQKLEDR LAAAAREKLA QASKESKEKQ LQAERKRKAA LFLQTLKNPL PEAEAGKIEE SPFSVEESST TPCPLLTGGR PLPTLEVKPP DRPSSKSKDP PREEEKEKKK KKHKKRSRTR SRSPKYHSSS KSRSRSHSKA KHSLPSAYRT VRRSRSRSRS PRRRAHSPER RREERSVPTA YRVSRSPGAS RKRTRSRSPH EKKKKRRSRS RTKSKARSQS VSPSKQAAPR PAAPAAHSAH SASVSPVESR GSSQERSRGV SQEKEAQISS AIVSSVQSKI TQDLMAKVRA MLAASKNLQT SAS (600-951 aa encoded by BC136678)

            Target Information

            Signal-induced proliferation associated-like protein 2 (SIPA1L2) is a member of the SIPA1 family of RapGAPs. Little is known of the role of the SIPA1L2 protein, but recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is likely that SIPA1L2 plays a role in embryo development and cell proliferation, possibly including oncogenesis.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            Bioinformatics

            Protein Aliases: Splicing factor, arginine/serine-rich 8; splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila); splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot, Drosophila homolog); splicing factor, suppressor of white-apricot family; Splicing factor, suppressor of white-apricot homolog; Suppressor of white apricot protein homolog

            View more View less

            Gene Aliases: SFRS8; SFSWAP; SWAP

            View more View less

            UniProt ID: (Human) Q12872

            View more View less

            Entrez Gene ID: (Human) 6433

            View more View less

            Function(s)

            RNA binding protein binding RNA splicing factor

            Process(es)

            alternative mRNA splicing, via spliceosome mRNA 5'-splice site recognition transcription, DNA-templated regulation of transcription, DNA-templated negative regulation of mRNA splicing, via spliceosome
            It has to be done as per old AB suggested Products section.
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