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Bethyl Laboratories
SH3KBP1 Binding Protein 1/SHKBP1 Polyclonal Antibody
Application
FIGURE: 1 / 1
SH3KBP1 Binding Protein 1/SHKBP1 Antibody (A304-891A) in IP
Detection of human SH3KBP1 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-SH3KBP1 antibody (Product # A304-891A) (lot 1) used for IP at 6 µg per reaction. SH3KBP1 was also immunoprecipitated by rabbit anti-SH3KBP1 antibody BL19185. For blotting im... View More
Product Details
A304-891A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 75 to 125 of Human SH3KBP1-binding protein 1.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat and Bovine
Target Information
Inhibits CBL-SH3KBP1 complex mediated down-regulation of EGFR signaling by sequestration of SH3KBP1. Binds to SH3KBP1 and prevents its interaction with CBL and inhibits translocation of SH3KBP1 to EGFR containing vesicles upon EGF stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: SETA-binding protein 1; SH3KBP1-binding protein 1
Gene Aliases: PP203; SB1; SHKBP1
UniProt ID: (Human) Q8TBC3
Entrez Gene ID: (Human) 92799
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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