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            • Primary Antibodies ›
            • SHC3 Antibodies

            Bioss

            SHC3 Polyclonal Antibody

            View all (12) SHC3 antibodies
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            Cite SHC3 Polyclonal Antibody

            • Antibody Testing Data (2)
            Application
            SHC3 Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 2

            SHC3 Antibody (BS-6199R) in WB

            Lane 1: rat heart lysates Lane 2: rat brain lysates probed with Anti SHC3 Polyclonal Antibody, Unconjugated (bs-6199R) at 1:200 in 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90 min in 37°C. Predicted band 65 kD. Observed band size: 65 kD.
            View Product

            SHC3 Antibody in Western Blot (WB)
            SHC3 Antibody in Western Blot (WB)

            Product Details

            BS-6199R

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:200
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            Assay-dependent
            -

            Immunohistochemistry (Frozen) (IHC (F))

            1:100-1:500
            -

            Immunocytochemistry (ICC/IF)

            1:50-1:200
            -

            ELISA (ELISA)

            1:500-1:1,000
            -
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            KLH conjugated synthetic peptide derived from human SHC3, amino acids 501-594.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Protein A

            Storage buffer

            0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA

            Contains

            0.02% ProClin 300

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Let us know so we can reference it here.
            Cite this product

            Bioinformatics

            Protein Aliases: N-Shc; Neuronal Shc; Protein Rai; SH2 domain protein C3; SHC (Src homology 2 domain containing) transforming protein 3; SHC-transforming protein 3; SHC-transforming protein C; Shc3 p51; src homology 2 domain-containing transforming protein C3; Src homology 2 domain-containing-transforming protein C3

            View more View less

            Gene Aliases: N-Shc; NSHC; RAI; SHC3; SHCC

            View more View less

            UniProt ID: (Human) Q92529, (Mouse) Q61120

            View more View less

            Entrez Gene ID: (Human) 53358, (Rat) 114858, (Mouse) 20418

            View more View less

            Function(s)

            signal transducer activity Ras guanyl-nucleotide exchange factor activity protein binding receptor tyrosine kinase binding phosphotyrosine binding receptor binding protein kinase binding scaffold/adaptor protein

            Process(es)

            MAPK cascade transmembrane receptor protein tyrosine kinase signaling pathway epidermal growth factor receptor signaling pathway Ras protein signal transduction central nervous system development learning or memory synaptic transmission, glutamatergic positive regulation of GTPase activity intracellular signal transduction signal transduction
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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            We're here to help

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