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Immunogen sequence: TTLSKSDAKK AASKTLLEKS QFSDKPVQDR GLVVTDLKAE SVVLEHRSYC SAKARDRHFA GDVLGYVTPW NSHGYDVTKV FGSKFTQISP VWLQLKRRGR EMFEVTGLHD VDQGWMRAVR KHAKGLHIVP RLLFEDWTYD DFRNVLDSED EIEELSKTVV QVAKNQHFDG FVVEVWNQLL SQKRVGLIHM LTHLAEALHQ ARLLALLVIP PAITPGTDQL GMFTHKEFEQ LAPVLDGFSL MTYDYSTAHQ PGPNAPLSWV RACVQVLDPK SKWRSKILLG LNFYGMDYAT SKDAREPVVG ARYIQTLKDH RPRMVWDSQA SEHFFEYKKS RSGRHVVFYP TLKSLQVRLE LARELGVGVS IWELGQGLDY FYDLL
SI-CLP detects human Stabilin-interacting chitinase like protein (SI-CLP), a novel member of the Glyco-18-domain containing protein family. SI-CLP is a secretory protein which is up-regulated in response to interleukin-4 and dexamethasone in activated macrophages. SI-CLP is also expressed by T- and B-lymphocytes, and by cells of monocytic and epithelial origin. SI-CLP is the ligand for stabilin-1, an intracellular sorting receptor which sorts SI-CLP into late endosomes and secretory lysosomes in activated macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chitinase domain-containing protein 1; FLJ42707; MGC3234; SI-CLP; stabilin-1 interacting chitinase-like protein; Stabilin-1-interacting chitinase-like protein
Gene Aliases: CHID1; GL008; PSEC0104; SB139; SI-CLP; SICLP
UniProt ID: (Human) Q9BWS9
Entrez Gene ID: (Human) 66005
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