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Invitrogen

SIDT2 Polyclonal Antibody

3 Published Figures

2 References

View all (2) SIDT2 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (6)
Published Figures (3)

Application

FIGURE: 1 / 9

SIDT2 Antibody (PA5-69064) in WB

Western blot analysis of SIDT2 on human fetal brain tissue lysate. The sample was probed with a SIDT2 polyclonal antibody (Product # PA5-69064) using a primary antibody dilution of 1.0 µg/mL.

SIDT2 Antibody in Surface plasmon resonance (SPR)

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Product Details

PA5-69064

Applications

Tested Dilution

Publications

Western Blot (WB)

0.2-1.0 µg/mL

View 2 publications 2 publications

Surface plasmon resonance (SPR)

Assay-dependent

Product Specifications

Species Reactivity

Human

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

synthetic peptide directed towards the N terminal region of human SIDT2

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2688610

Product Specific Information

This target displays homology in the following species: Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%

Target Information

The SID1 transmembrane family member (SIDT2) is a highly glycosylated, multipass transmembrane protein that localizes to the lysosomal membrane. SIDT2 is highly expressed in liver, brain and kidney, with no or little expression in skeletal muscles, heart or other tissues. Little is known of the function of SIDT2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

SIDT2 Associates with Apolipoprotein A1 (ApoA1) and Facilitates ApoA1 Secretion in Hepatocytes.

Cells

Sampieri A,Asanov A,Méndez-Acevedo KM,Vaca L

PA5-69064 was used in Western Blot to provide evidence of a novel role for SIDT2 as a protein forming a complex with ApoA1 and enhancing its secretion to the extracellular space.

Tue Sep 26 00:00:00 UTC 2023

Sidt2 is a key protein in the autophagy-lysosomal degradation pathway and is essential for the maintenance of kidney structure and filtration function.

Cell death & disease

Geng MY,Wang L,Song YY,Gu J,Hu X,Yuan C,Yang M,Pei WJ,Zhang Y,Gao JL

Published figure using SIDT2 polyclonal antibody (Product # PA5-69064) in Western Blot

Sat Dec 18 00:00:00 UTC 2021

Sidt2 is a key protein in the autophagy-lysosomal degradation pathway and is essential for the maintenance of kidney structure and filtration function.

Cell death & disease

Geng MY,Wang L,Song YY,Gu J,Hu X,Yuan C,Yang M,Pei WJ,Zhang Y,Gao JL

Published figure using SIDT2 polyclonal antibody (Product # PA5-69064) in Western Blot

Sat Dec 18 00:00:00 UTC 2021

Bioinformatics

Protein Aliases: SID1 transmembrane family member 2; SID1 transmembrane family, member 2

Gene Aliases: CGI-40; PSEC0072; SIDT2; UNQ685/PRO1325

UniProt ID: (Human) Q8NBJ9

Entrez Gene ID: (Human) 51092

Function(s)

Process(es)

cell morphogenesis type B pancreatic cell development response to glucose dsRNA transport glucose homeostasis type B pancreatic cell proliferation regulation of insulin secretion involved in cellular response to glucose stimulus

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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