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Product Details
22711-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SLAMF6 Fusion Protein Ag18517 (40-332 aa encoded by BC114495)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.49 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LPLEFPAGE KVNFITWLFN ETSLAFIVPH ETKSPEIHVT NPKQGKRLNF TQSYSLQLSN LKMEDTGSYR AQISTKTSAK LSSYTLRILR QLRNIQVTNH SQLFQNMTCE LHLTCSVEDA DDNVSFRWEA LGNTLSSQPN LTVSWDPRIS SEQDYTCIAE NAVSNLSFSV SAQKLCEDVK IQYTDTKMIL FMVSGICIVF GFIILLLLVL RKRRDSLSLS TQRTQGPAES ARNLEYVSVS PTNNTVYASV THSNRETEIW TPRENDTITI YSTINHSKES KPTFSRATAL DNVV (40-332 aa encoded by BC114495)
Target Information
Ly108 is the mouse homologue of human SLAMF6 (signaling lymphocyte activation molecule family member 6). Mouse Ly108 is expressed on NK, B cells, and T cells. Activation of Ly108 receptor enhances NK cell activity and IFN-gamma expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Activating NK receptor; CD352; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTB-A; NTBA receptor; SLAM family member 6
Gene Aliases: CD352; KALI; KALIb; Ly108; NTB-A; NTBA; SF2000; SLAMF6; UNQ6123/PRO20080
UniProt ID: (Human) Q5TAS6
Entrez Gene ID: (Human) 114836
natural killer cell differentiation
natural killer cell proliferation
positive regulation of interferon-gamma production
positive regulation of interleukin-17 production
innate immune response
positive regulation of natural killer cell mediated cytotoxicity
regulation of immune response
T-helper 17 cell lineage commitment
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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