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Product Details
6571-MSM3-P1ABX
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2, kappa
Class
Monoclonal
Type
Antibody
Clone
SLC18A2/7983
Immunogen
Recombinant fragment of human SLC18A2 protein (exact sequence is proprietary)
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control: adrenal gland or tonsil. Human brain
Cellular Location: Cytoplasm. Vesicle membrane.
Target Information
VMAT2 is involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. It is a requisite for vesicular amine storage prior to secretion via exocytosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MGC120477; MGC120478; MGC26538; monoamine neurotransmitter transporter; monoamine transporter; solute carrier family 18 (vesicular monoamine transporter), member 2; solute carrier family 18 (vesicular monoamine), member 2; Solute carrier family 18 member 2; Synaptic vesicular amine transporter; VAT2; vesicle monoamine transporter type 2; vesicle monoamine/H+ antiporter; Vesicular amine transporter 2; Vesicular monoamine transporter 2
Gene Aliases: SLC18A2; SVAT; SVMT; VAT2; VMAT2
UniProt ID: (Human) Q9H3P6
Entrez Gene ID: (Human) 6571
response to amphetamine
serotonin transport
chemical synaptic transmission
neurotransmitter secretion
aging
locomotory behavior
response to herbicide
post-embryonic development
response to zinc ion
aminergic neurotransmitter loading into synaptic vesicle
monoamine transport
dopamine transport
insulin secretion
endocytic recycling
cellular response to drug
sequestering of neurotransmitter
response to cocaine
glucose homeostasis
response to starvation
response to corticosterone
negative regulation of neurotransmitter transport
transmembrane transport
cellular response to ammonium ion
neurotransmitter loading into synaptic vesicle
negative regulation of reactive oxygen species biosynthetic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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