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Immunogen sequence: MAVKVQTTKR GDPHELRNIF LQYASTEVDG ERYMTPEDFV QRYLGLYNDP NSNPKIVQLL AGVADQTKDG LISYQEFLAF ESVLCAPDSM FIVAFQLFDK SGNGEVTFEN VKEIFGQTII HHHIPFNWDC EFIRLHFGHN RKKHLNYTEF TQFLQELQLE HARQAFALKD KSKSGMISGL; Positive Samples: Raji, U-87MG, B-cell, SKOV3, HeLa, Mouse heart, Mouse brain, Mouse liver, Rat heart; Cellular Location: Mitochondrion inner membrane, Multi-pass membrane protein
This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in the gene encoding this protein may be associated with risk of autism.
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Protein Aliases: Araceli hiperlarga; Aralar; calcium binding mitochondrial carrier superfamily member Aralar1; calcium-binding mitochondrial carrier protein Aralar1; Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial; Mitochondrial aspartate glutamate carrier 1; solute carrier family 25 (aspartate/glutamate carrier), member 12; solute carrier family 25 (mitochondrial carrier, Aralar), member 12; Solute carrier family 25 member 12; solute carrier family 25, member 12
Gene Aliases: 2610002D09Rik; AGC1; AI839531; ARALAR; ARALAR1; B230107K20Rik; BB129864; RGD1561141; SLC25A12
UniProt ID: (Human) O75746, (Mouse) Q8BH59
Entrez Gene ID: (Human) 8604, (Mouse) 78830, (Rat) 362145
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