Product References
SLC25A46 promotes mitochondrial fission and mediates resistance to lipotoxic stress in INS-1E insulin-secreting cells.
Journal of cell science
Santo-Domingo J,Lassueur S,Galindo AN,Alvarez-Illera P,Romero-Sanz S,Caldero-Escudero E,de la Fuente S,Dayon L,Wiederkehr A
Sat Apr 15 00:00:00 EDT 2023
Reanalysis of Exome Data Identifies Novel SLC25A46 Variants Associated with Leigh Syndrome.
Journal of personalized medicine
Li Q,Madden JA,Lin J,Shi J,Rosen SM,Schmitz-Abe K,Agrawal PB
Thu Dec 02 00:00:00 EST 2021
Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1.
Science advances
Antico O,Ordureau A,Stevens M,Singh F,Nirujogi RS,Gierlinski M,Barini E,Rickwood ML,Prescott A,Toth R,Ganley IG,Harper JW,Muqit MMK
Fri Nov 12 00:00:00 EST 2021
A High-Density Human Mitochondrial Proximity Interaction Network.
Cell metabolism
Antonicka H,Lin ZY,Janer A,Aaltonen MJ,Weraarpachai W,Gingras AC,Shoubridge EA
Tue Sep 01 00:00:00 EDT 2020
Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria.
Molecular biology of the cell
Steffen J,Vashisht AA,Wan J,Jen JC,Claypool SM,Wohlschlegel JA,Koehler CM
Wed Mar 01 00:00:00 EST 2017
SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome.
EMBO molecular medicine
Janer A,Prudent J,Paupe V,Fahiminiya S,Majewski J,Sgarioto N,Des Rosiers C,Forest A,Lin ZY,Gingras AC,Mitchell G,McBride HM,Shoubridge EA
Thu Sep 01 00:00:00 EDT 2016
Loss of function of SLC25A46 causes lethal congenital pontocerebellar hypoplasia.
Brain : a journal of neurology
Wan J,Steffen J,Yourshaw M,Mamsa H,Andersen E,Rudnik-Schöneborn S,Pope K,Howell KB,McLean CA,Kornberg AJ,Joseph J,Lockhart PJ,Zerres K,Ryan MM,Nelson SF,Koehler CM,Jen JC
Tue Nov 01 00:00:00 EDT 2016
Loss of function of SLC25A46 causes lethal congenital pontocerebellar hypoplasia.
Brain : a journal of neurology
Wan J,Steffen J,Yourshaw M,Mamsa H,Andersen E,Rudnik-Schöneborn S,Pope K,Howell KB,McLean CA,Kornberg AJ,Joseph J,Lockhart PJ,Zerres K,Ryan MM,Nelson SF,Koehler CM,Jen JC
Tue Nov 01 00:00:00 EDT 2016